Targeted sequencing of SMO and AKT1 in anterior skull base meningiomas
نویسندگان
چکیده
منابع مشابه
Fungal infection of the sinus and anterior skull base
Abstract Background: Invasive fungal infection is an opportunistic infection caused commonly by mucoraccae and aspergillus. It mostly occurs in patients with underlying disease. Since it has a high mortality and morbidity rate, considering a treatment strategy seems necessary. Objective: Since there has not been a clear protocol for treating these patients, we decided to establish...
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With recent advances in surgical technology such as preoperative imaging, neuro-monitoring, and surgical instruments, the surgical resectability of intracranial meningiomas has increased over the last two decades. This study reviewed clinical articles regarding the surgical treatment of meningiomas to clarify the role of surgical excision, with a focus on skull base meningiomas. We sub-classifi...
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AIM Midline anterior skull base meningiomas include olfactory groove meningiomas (OGMs), Tuberculum Sellae meningiomas (TSMs), and planum sphenoidale meningiomas (PSMs). The main surgical challenge in treating these lesions is to excise the tumor totally without causing mortality or morbidity. Studying the clinical patterns and the surgical outcomes of these lesions. MATERIAL AND METHODS Thir...
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Meningiomas comprise approximately 20% of adult primary intracranial neoplasms. Of these, benign meningiomas are known to have an indolent growth pattern, usually without infiltration into adjacent nervous tissue. Because meningiomas have a well-circumscribed character, surgery has historically been the preferred treatment when total resection can be achieved with reasonable morbidity. Surgical...
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Meningiomas located in the region of the base of skull are difficult to access. Complex combined surgical approaches are more likely to achieve complete tumor removal, but frequently at a cost of treatment related high morbidity. Local control following subtotal excision of benign meningiomas can be improved with conventional fractionated external beam radiation therapy with a reported 5-year p...
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ژورنال
عنوان ژورنال: Journal of Neurosurgery
سال: 2017
ISSN: 0022-3085,1933-0693
DOI: 10.3171/2016.8.jns161076